Abstracting and Indexing

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Background: Perforation peritonitis is a common emergency in Indian surgery, associated with high numbers of irreversible harm and death. It’s important to know what risks patients face and how they respond to treatment in order to manage conditions well.

Objective: The objective of this study is to look at risk factors and results in patients admitted to a tertiary care center in India with perforation peritonitis.

Methods: This prospective observational study was conducted over a year (Jan 2025- Dec 2025) at Katihar Medical College. We included patients found to have perforation peritonitis and who were operated on using exploratory laparotomy. What we collected included demographic traits, symptoms, what was discovered during the procedures and outcomes after treatment. Experts used statistical methods to spot risk factors that affect people’s likelihood of catching or dying from the disease.

Results: Among the 120 enrolled patients, the ratio of males to females was 2.33:1. Perforation most frequently resulted from peptic ulcer disease 48.3% and typhoid fever 21.7%. Factors increasing the risk for increased illness and death were delayed arrival to the hospital, low blood pressure on admission, lower albumin levels and existing chronic liver problems. The overall mortality rate was 14.2%.

Conclusion: The faster the perforation is recognized and surgery is performed, the better the outcome. Taking action on modifiable risks may decrease the risk of serious problems in patients.