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Asthma Phenotypes in Children: Implications for Personalized Treatment Approaches
Article Information
The clinical symptoms, inflammatory processes and reactions to medication vary greatly in children with asthma. The idea of asthma phenotypes is to group these different clinical patterns to help with diagnosis, prediction of the future and treatment. This review looks at the latest knowledge about pediatric asthma phenotypes, drawing on both Indian and worldwide research. Major types of asthma such as allergic, non-allergic, early-onset, lateonset and severe asthma, are discussed and their main symptoms and causes are highlighted. Treatment plans designed for these phenotypes by using targeted biologics and anti-inflammatory therapies are discussed. It is also pointed out that pediatric asthma phenotyping in India needs improvement and researchers are urged to use longitudinal and molecular methods to better classify patients and provide better care. Tailored care for asthma in children could improve their condition, lower the risk of attacks and raise their quality of life.