Abstracting and Indexing

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Introduction: People with Type 2 Diabetes Mellitus (T2DM) are more likely to experience cognitive deterioration, which can negatively affect their quality of life. Examining the prevalence of cognitive deterioration in T2DM individuals was the goal of this investigation.

Methods: Eighty participants in the study were allotted into two groups: forty T2DM patients (test group) and forty non-diabetic people (control group). The Montreal Cognitive Assessment (MoCA) was used to estimate cognitive function. We gathered and examined demographic information, BMI, smoking status, and educational attainment. Descriptive statistics, chi-square tests, and multivariate regression analysis using SPSS Version 23 were among the statistical studies performed.

Results: The test group had a notably lower MoCA score (22.1 ± 4.3) compared to the control group (27.5 ± 2.9), indicating cognitive impairment prevalence of 65% among T2DM patients versus 15% in controls (p < 0.001). Higher BMI was negatively correlated with cognitive performance (β = -0.65, p < 0.001), while education level was positively correlated (β = 0.40, p < 0.01). Smoking status showed a trend toward significance, with current smokers displaying lower cognitive scores.

Conclusion: The study highlights a significant prevalence of cognitive decline among T2DM patients in Mysuru, strongly associated with higher BMI, lower education levels, and smoking status.

Recommendations: Healthcare providers should prioritize cognitive assessments in T2DM management and implement lifestyle interventions targeting obesity, smoking cessation, and educational support to mitigate cognitive impairment in this population.

Keywords: Type 2 Diabetes Mellitus, Cognitive Decline, Montreal Cognitive Assessment, Body Mass Index, Smoking, Education Level